The Cell Squeeze® Technology
We physically squeeze cells at high speeds through a microfluidic chip, temporarily opening the cell membrane and enabling biologic material of interest, or cargo, to diffuse into the cell before the membrane reseals. This technology allows us to create a broad pipeline of product candidates for different diseases.
The Cell Squeeze® technology enables rapid, scalable, and economic production of our cell therapies.
The production time for our current product candidates is under 24 hours, with a vein-to-vein time of approximately one week. SQZ therapies are administered to patients through a simple syringe push and without harsh pre-conditioning.
The Cell Squeeze® technology allows for robust parallelization and scale up. A single chip can contain hundreds of parallel channels that enable us to process over 10 billion cells per minute.
Our manufacturing process is designed to create treatments at a fraction of the cost of other cell therapies. We believe that eliminating the need for viral vectors and multi-day manufacturing could cut costs dramatically relative to current cell therapies and enable expansion into areas where other approaches are cost prohibitive.