T Cell Engineering

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T Cell Engineering

T cells are some of our best tumor killers. Here, we look at how patient T cells can be used to generate TIL, TCR, and CAR-T therapies to fight a tumor.

Posted August 7, 2021 · Follow Us:

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All Comics in the Oncology Series

Checkpoint Inhibitors

Checkpoint Inhibitors (CPIs) are an important immuno-therapy approach for patients with certain cancers. In this #HowCellsWork story, we examine how different types of CPIs work to allow T cells to attack tumors. Check out our cell stories here:

Jun 24, 2022

The Link Between HPV and Cervical Cancer

At SQZ Biotechnologies, we are committed to the fight against this disease with our first clinical program. In this #HowCellsWork episode, we examine HPV infection, cancer cell formation, and the important role of PAP smears for early diagnosis.

Feb 5, 2022

MHC-II vs MHC-I Presentation

It’s important to tailor presentations to your target audience - even in the immune system. Different presentation mechanisms in APCs prioritize CD8 Killer T cells versus CD4 Helper T cells. In this #HCW episode, we illustrate how prioritizing presentation to CD8 Killer T cells leads to stronger anti-tumor effects.

Feb 5, 2022

DC Engineering

In this story of our oncology series, we explore how scientists have tried to engineer dendritic cells, the generals of the immune system.

Aug 12, 2021

Macrophage Engineering

In this story, we move to the hungry cell of the immune system: Macrophages. Macrophages are another important layer of our innate immune system and may be utilized in different ways to address disease. CAR-Macrophages are one commonly discussed approach.

Aug 12, 2021

NK Engineering

NK Cells are the non-antigen specific, innate killers of the immune system. These front-line killers of tumors and virally-infected cells may not have some of the features of a T cell, but they are an important part of our immune system!

Aug 8, 2021

T Cell Engineering

T cells are some of our best tumor killers. Here, we look at how patient T cells can be used to generate TIL, TCR, and CAR-T therapies to fight a tumor.

Aug 7, 2021